To use, shake well before and occasionally during use. Administer 5cc dose subcutaneously. Administer three doses to each animal at four-to-six-week intervals. Booster doses are timed to the lactation cycle. Either of two protocols (see above) using three doses are effective: at dry off, mid dry off, and 3-4 weeks fresh OR alternatively at dry off, 3-4 weeks fresh, and 7-8 weeks fresh. Do not vaccinate within two weeks of parturition.